Post Doctoral Scholar
Penn State University
- College of Medicine at the Milton S. Hershey Medical Center
- Date Announced:
- Date Closing:
- Job Number:
- Cancer Institute
The Penn State Cancer Institute is seeking a Post-Doctoral Scholar to work in the laboratory of Dr. Patrick Ma. The applicant will perform clinical translational research in cancer biology, signaling, multi-omics cancer bioinformatics, targeted and immunotherapy and their mechanisms of drug resistance, with special emphasis on thoracic malignancies. Independently design and perform experiments requiring highly specialized techniques in cancer cellular/molecular biology and cancer immunology. These will consist of In vivo studies using both immunocompromised (e.g. nude mouse, NSG mouse) and immunocompetent mouse models of cancer, including adoptive transfer of primary T cells. Molecular and cellular assays such as MTS viability assay, western blot, soft agar assay, cell invasion assay. Isolation and analysis of tumor infiltrating lymphocytes using multiplex single-cell analysis techniques. Quantification of gene expression by qRT-PCR and preparation of samples for RNAseq and other genomics, proteomics and epigenomics profiling experiments. Translational studies involving archival and fresh human tumor biopsied tissues and cell lines, and establishment of preclinical animal models using patient-derived xenografts method. Management of clinical-pathologic database on translational research project projects involving patients’ tissue and blood samples. Perform multicolor flow cytometry experiments. Attend and present at lab meetings and external national/international conferences. Perform manual or computer-assisted data analysis, including the use of bioinformatics software; accurately record procedures used and results obtained from all experiments conducted; summarize results as a primary or a co-author in the form of manuscripts targeted towards high-visibility research journals or posters targeted towards scientific conferences. Assist in lab stewardship, which may include maintaining cell cultures, manages safety assessment documents and databases, maintaining lab and equipment, keeping accurate inventory of lab assets, ordering supplies, and follow-up on working conditions of lab equipment and usage. Develop new techniques and protocols by consulting various sources (articles, faculty, manufacturers, etc.). Maintain professional growth and development by reading current research literature, attending courses, seminars, and presenting research at conferences. Advise, educate, and train other lab personnel on area(s) of expertise.
These salary bands have been established to provide salary guidelines for staff positions.