Penn State University
- College of Medicine at the Milton S. Hershey Medical Center
- Campus City:
- Hershey, PA
- Date Announced:
- Date Closing:
- open until filled
- Job Number:
- Work Unit:
- Penn State College of Medicine
- Cellular and Molecular Physiology
A NIH-funded post-doctoral position is available in Dr. Shengyu Yang’s lab at the Penn State College of Medicine to study the role of mitochondrial actin filaments in cancer metastasis. Our goal is to reveal how the dysregulated actin cytoskeleton in metastatic cancer cells controls mitochondrial oxidative phosphorylation by remodeling the mitochondrial actin filaments. This project is built on our recent discoveries that the actin cytoskeleton remodeling in metastatic cancer cells is able to control mitochondrial metabolism through regulating the homeostasis of mtDNA and the biogenesis of mitochondrial respiratory chain. Biochemistry, cell biology, live cell imaging techniques, genetically engineered mouse models and patient-derived xenografts will be employed in the study. The successful applicant will be a highly motivated recent graduate with a Ph.D. or equivalent degree and will have expertise in cell biology, biochemistry, molecular biology or related fields. Experience with fluorescence imaging, super-resolution microscopy and genetically engineered mouse models is desirable but not required. The research in Dr. Yang’s lab is well funded by grants from the National Cancer Institute, Department of Defense and the Elsa U. Pardee Foundation. The Penn State College of Medicine Campus is located in Hershey, PA. Hershey is a quiet, family friendly town with affordable living expenses and easy access to major metropolitan areas (e.g. Philadelphia, Washington DC, and New York City). Please send cover letter, CV and contact information for three references.
These salary bands have been established to provide salary guidelines for staff positions.